This post summarizes my upcoming talk for the Living in Space Track at ISDC 2024 taking place in Los Angeles May 23 – 26. The presentation is a distillation of several posts on the Gravity Prescription about which I’ve written over the years.
Lets start with a couple of basic definitions. First, what exactly is a space settlement? The National Space Society defined the term with much detail in an explainer by Dale L. Skran back in 2019. I’ve extracted this excerpt with bolded emphasis added:
Space Settlement is defined as:
“… a habitation in space or on a celestial body where families live on a permanent basis, and that engages in commercial activity which enables the settlement to grow over time, with the goal of becoming economically and biologically self-sustaining …”
The point here is that people will want to have children wherever their families put down roots in space communities. Yes, a “settlement” could be permanent and perhaps inhabited by adults that live out the rest of there lives there, such as in a retirement community. But these are not biologically self-sustaining in the sense that settlers have offspring that are conceived, born and raised there living out healthy lives over multiple generations.
Next we should explain what is meant by the Gravity Prescription (GRx). First coined by Dr. Jim Logan, the term refers to the minimum “dosing” of gravity (level and duration of exposure) to enable healthy conception, gestation, birth and normal, viable development to adulthood as a human being…over multiple generations. It should be noted that the GRx can be broken down into at least three components: the levels needed for pregnancy (conception through birth), early child development, and adulthood. The focus of this discussion is primarily on the GRx for reproduction.
We should also posit some basic assumptions. First, with the exception of the GRx, all challenges expected for establishment of deep space settlements can be solved with engineering solutions (e.g. radiation protection, life support, power generation, etc…). The one factor that cannot be easily changed impacting human physiology after millions of year of evolution on Earth is gravity. We may find it difficult or even impossible to stay “healthy enough” under hypogravity conditions on the Moon or Mars, assuming all other human factors are dealt with in habitat design.
Lets dive into what we know and don’t know about the GRx. Several decades of human spaceflight have produced an abundance of data on the deleterious effects of microgravity on human physiology, not the least of which are serious reduction in bone and muscle mass, ocular changes, and weakening of the immune system – there are many more. So we know microgravity is not good for human health after long stays. Clearly, having babies under these conditions would not be ethical or conducive for long term settlement.
The first studies carried out on mammalian reproduction in microgravity took place in the early 1990s aboard the Space Shuttle in a couple of experiments on STS-66 and STS-70. 10 pregnant rats were launched at midpregnancy (9 days and 11 days, respectively) on each flight and landed close to the (22 day) term. The rat pups were born 2 days after landing and histology of their brain tissue found spaceflight induced abnormalities in brain development in 70% of the offspring.
It was not until 2017 that the first mammalian study of rodents with artificial gravity was performed on the ISS. Although not focused on reproduction, the Japan Aerospace Exploration Agency (JAXA) performed a mouse experiment in their Multiple Artificial-gravity Research System (MARS) centrifuge comparing the impact of microgravity to 1g of spin gravity. The results provided the first experimental evidence that mice exposed to 1g of artificial gravity maintained the same bone density and muscle weight as mice in a ground control group while those in microgravity had significant reductions.
In 2019 JAXA carried out a similar study in the MARS centrifuge adding lunar gravity levels to the mix. This study found that there were some benefits to the mice exposed to 1/6g in that Moon gravity helped mitigate muscle atrophy, but it did not prevent changes in muscle fiber or gene expression.
Just last year, a team led by Dr. Mary Bouxsein at Harvard Medical School conducted another adult mouse study on the MARS centrifuge comparing microgravity, .33g, .67g and 1g. They found that hind quarter muscle strength increased commensurate with the level artificial gravity concluding, not surprisingly, that spaceflight induced atrophy can be mitigated with centrifucation. The results were reported at the American Society for Gravitational and Space Research last November.
Returning to mammalian reproduction in space, an interesting result was reported last year in the journal Cell from an experiment by Japanese scientists at the University of Yamanashi carried out on the ISS in 2019. The team, headed up by Teruhiko Wakayama, devised a way to freeze mouse embryos post conception and launch them into space where they were thawed by astronauts and allowed to develop in microgravity. Control samples were cultured in 1g artificial gravity on the ISS and Earth normal gravity on the ground. The mouse embryos developed into blastocysts and showed evidence of cell differentiation/gene expression in microgravity after 4 days. The researchers claimed that the results indicated that “Mammals can thrive in space”. This conclusion really can’t be substantiated without further research.
Which brings us to several unknowns about reproduction in space. SSP has explored this topic in depth through an interview with Alex Layendecker, Director of the Astrosexological Research Institute. Yet to be studied in depth is (a) conception, including proper transport of a zygote through the fallopian tube to implantation in the uterus. Less gravity may increase the likelihood of ectopic pregnancy which is fatal for the fetus and could endanger the life of the mother; (b) full gestation through all stages of embryo development to birth; and (c) early child development and maturation to adulthood in hypogravity. All these stages of mammalian reproduction need to be validated through ethical clinical studies on rodents progressing to higher primate animal models before humans can know if having children in lower gravity conditions on the Moon or Mars will be healthy and sustainable over multiple generations.
Some space advocates for communities on the Moon or Mars have downplayed the importance of determining the GRx for reproduction with the logic that a fetus in a woman’s uterus on Earth is in neutral buoyancy and thus is essentially weightless. Therefore, why does gravity matter? I discussed this question with Dr. Layendecker and he had the following observations paraphrased here: True, gravity may have less of an impact in the first trimester. But on the cellular level, cytoskeletal development and proper formation/organization of cells may be impacted from conception to birth. Gravity helps orient the baby for delivery in the last trimester and keeps the mother’s uterine muscles strong for contractions/movement of the baby through the birth canal. There are many unknowns on what level of gravity is sufficient for normal development from conception to adulthood.
Why does all this matter? Ethically determining the right level of gravity for healthy reproduction and child development will inform where families can safely settle space. The available surface gravities of bodies where we can establish communities in space cluster near Earth, Mars and Moon levels. These are our only GRx options on solar system bodies.
The problem is that we don’t yet know whether we can remain healthy enough on bodies with gravity equivalent to that on the Moon or Mars, so we can’t select realistic human destinations or formulate detailed plans until we acquire this knowledge. Of course we can always build rotating settlements in free space with artificial gravity equivalent to that on Earth. Understanding the importance of the GRx and determining its value could change the strategy of space development in terms of both engineering and policy decisions. The longer we delay, the higher the opportunity costs in terms of lost time from failure to act.
What are these opportunity cost lost opportunities? Clearly, at the top of Elon Musk’s list is “Plan B” for humanity, i.e. a second home in case of cataclysmic disaster such as climate change, nuclear war, etc. This drives his sense of urgency. From Gerard K. O’Neill’s vision in The High Frontier, virtually unlimited resources in space could end hunger and poverty, provide high quality living space for rapidly growing populations, achieve population control without war, famine, or dictatorships. And finally, increase freedom and the range of options for all people.
If humans can’t have babies in less than Earth’s gravity then the Moon and Mars may be a bust for long term (biologically sustainable) space settlement. There will be no biologically sustainable cities with millions of people on other worlds unless they can raise families there.
Spin gravity rotating space settlements providing 1g artificial gravity may be the only alternative. If Elon Musk knew that the people he wants to send to Mars can’t have children there, would he change his plans for a self-sustaining colony on that planet? Having and raising children is obviously important to him. As Walter Isaacson wrote in his recent biography of Musk, “He feared that declining birthrates were a threat to the long-term survival of human consciousness.”
So how could he determine the GRx quickly? One solution would be to fund a partial gravity facility in low Earth orbit to run ethical experiments on mammalian reproduction in hypogravity. Joe Carroll has been refining a proposal for such a facility, a dual dumbbell Moon/Mars low gravity laboratory which SSP has covered, that could also be marketed as a tourist destination. Spinning at 1.5 rpm, the station would be constructed from a combination of Starship payload-sized habitats tethered by airbeams allowing shirt sleeve access to different gravity levels. Visitors would be ferried to the facility in Dragon capsules and could experience 3 gravity levels with various tourist attractions. The concept would be faster, cheaper, safer and better than establishing equivalent bases on the Moon or Mars to quickly learn about the GRx. The facility would be tended by crews at both ends that live & collect health data for up to a year or more. And of course, ethical experiments on the GRx for mammalian reproduction would be carried out, first on rodents and then progressing to higher primates if successful.
What if these experiments determine that having children in lower gravity is not possible and our only path forward are free-space rotating settlements? Physics and human physiology require that they be large enough for settlers to tolerate a 1g spin rate to prevent disorientation. As originally envisioned by O’Neill, the diameter of his Island One space settlement would be about 500 meters.
As originally proposed, these settlements would be located outside the Earth’s magnetic field at the L5 Earth-Moon Lagrange Point necessitating that they be shielded with enormous amounts of lunar regolith to protect occupants from radiation. Their construction requires significant technology development and infrastructure (e.g. mass drivers on the Moon, automated assembly in space, advances in robotics, power sources, etc…). Much of this will eventually be done anyway as space development progresses…however, knowing the GRx (if it is equal to 1g) may foster a sense of urgency.
Some may take the alternative viewpoint that if we know that Earth’s gravity works just fine we could proceed directly to free-space settlements if we could overcome the mass problem. This is the approach Al Globus and Tom Marotta took in their book The High Frontier: An Easier Way with Kalpana One, a 450m diameter cylindrical rotating free-space settlement located in equatorial low Earth orbit (ELEO) protected by our planet’s magnetic field, thereby reducing the mass significantly because there would be far less need for heavy radiation shielding.
But there may be an even easier way. Kasper Kubica has proposed a 10 year roadmap to the $10M condo in ELEO based on Kalpana Two, a scaled down version of the orbital settlement described by Al Globus in a 2017 Space Review article.
Even though these communities would be lower mass, they will still require significant increases in launch rates to place the needed materials in LEO, especially near the equator. Offshore spaceports, like those under development by The Spaceport Company, could play a significant role in this infrastructure. Legislation providing financial incentives to municipalities to build spaceports would be helpful, such as The Secure U.S. Leadership in Space Act of 2024 introduced in Congress last month. The new law (not yet taken up in the Senate) would amend the IRS Code to allow spaceports to issue tax-exempt Muni bonds for infrastructure improvements.
Wouldn’t orbital debris present a hazard for settlements in ELEO? Definitely yes, and the National Space Society is shaping policy in this area. The best approach is to emphasize “light touch” regulatory reform on salvage rights, with protection and indemnity of the space industry to encourage recycling and debris removal. Joe Carroll has suggested a market-based approach that would impose parking fees for high value orbits, which would fund a bounty system for debris removal. This system would incentivize companies like CisLunar Industries, Neumann Space and Benchmark Space Systems, firms that are developing space-based processes to recycle orbital debris into useful commodities such as fuel and structural components.
Further down the road in technology development and deeper into space, advances in artificial intelligence and robotics will enable autonomous conversion of asteroids into rotating space settlements, as described by David Jensen in a paper uploaded to arXiv last year. This approach significantly reduces launch costs by leveraging in situ resource utilization. Initially, small numbers of “seed” tool maker robots are launched to a target asteroid along with supplemental “vitamins” of components like microprocessors that cannot be easily fabricated until technology progresses, to complete the machines. These robotic replicators use asteroid materials to make copies of themselves and other structural materials eventually building out a rotating space settlement. As the technology improves, the machines eventually become fully self-replicating, no longer requiring supplemental shipments from Earth.
Leveraging AI to enable robots to build space settlements removes humans from the loop initially, eliminating risk to their health from exposure to radiation and microgravity. Send it the robot home builders – families then safely move in later. There are virtually unlimited supplies in the asteroid belt to provide feedstock to construct thousands of such communities.
If rotating space settlements with Earth-normal gravity become the preferred choice for off-Earth communities, where would be the best location, the prime real estate of the solar system? Jim Logan has identified the perfect place with his Essential Seven Settlement Criteria.
- Low Delta-V – enabling easy access with a minimum of energy
- Lots of RESOURCES … obviously!
- Little or No GRAVITY WELL – half way to anywhere in the solar system
- At or Near Earth Normal GRAVITY for
People, Plants and Animals - like what evolved on Earth
- Natural Passive 24/7 RADIATION Protection – for healthy living
- Permit Large Redundant Ecosystem(s) – for sustenance and life support
- Staging Area for Exploration and Expansion
(including frequent, recurrent launch windows)
Using this criteria, Logan identified Deimos, the outermost moon of Mars, as the ideal location. As discussed above, AI and robotic mining technology improvements will enable autonomous boring machines to drill a 15km long core through this body with a diameter around 500 meters – sized for an Island One space settlement to fit perfectly.
In fact, 11 Island One space colonies (minus the mirrors) strung end to end through this tunnel would provide sea level radiation protection and Earth normal artificial gravity for thousands of healthy settlers.
In conclusion, the GRx for reproduction will inform where biologically self-sustaining healthy communities can be established in space. If we find that the GRx is equal to Earth’s normal level, free-space settlements with artificial gravity will be the safest and healthiness solution for humans to live and thrive throughout the solar system. The sooner we determined the GRx the better, for current plans for settling the Moon or Mars may need to be altered to consider rotating space colonies, which will require significant infrastructure development and regulatory reform. Alternatively, since we know Earth’s gravity works just fine, we may choose to skip determination of the GRx and start small with Kalpana in low Earth orbit. Eventually, artificial intelligence will enable safe, autonomous self-assembly of space settlements from asteroids. The interior of Deimos would be the perfect place to build safe, healthy and biologically self-sustaining space settlements.